Publications

Nature Genetics cover showing skin pigmentation diversity in Africans

Unravelling the molecular mechanisms of skin color diversity in Africans

Feng Y, Tishkoff SA.

Nature Genetics. 2024.

PMID: 38238631 | DOI: 10.1038/s41588-023-01643-0

Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans

Feng Y, Xie N, Inoue F, Fan S, Saskin J, Zhang C, Zhang F, Hansen MEB, Nyambo T, Mpoloka SW, Mokone GG, Fokunang C, Belay G, Njamnshi AK, Marks MS, Oancea E, Ahituv N, Tishkoff SA.

Nature Genetics. 2024; 56(2):258-272.

PMID: 38200130 | DOI: 10.1038/s41588-023-01626-1

Cell journal cover showing African population evolution

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

Fan S, Spence JP, Feng Y, Hansen MEB, Terhorst J, Beltrame MH, Ranciaro A, Hirbo J, Beggs W, Thomas N, Nyambo T, Mpoloka SW, Mokone GG, Njamnshi A, Folkunang C, Meskel DW, Belay G, Song YS, Tishkoff SA.

Cell. 2023; 186(5):923-939.

PMID: 36868214 | DOI: 10.1016/j.cell.2023.01.042

Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection

Zhang C, Verma A, Feng Y, Melo MCR, McQuillan M, Hansen M, Lucas A, Park J, Ranciaro A, Thompson S, Beggs W, Berens AJ, Campbell MC, Garrigan D, Rubel MA, Blum MGB, Daya M, Fagundes NJR, Gignoux CR, Granka J, Hollfelder N, Kenny EE, Mallick S, Metspalu M, Micheletti SJ, Nyambo T, Padilla-Guerrero IE, Patin E, Quintana-Murci L, Sezgin E, Tishkoff SA.

Proceedings of the National Academy of Sciences. 2022; 119(21):e2123000119.

PMID: 35580180 | DOI: 10.1073/pnas.2123000119

Evolutionary genetics of skin pigmentation in African populations

Feng Y, McQuillan MA, Tishkoff SA.

Human Molecular Genetics. 2021; 30(R1):R88-R97.

PMID: 33438000 | DOI: 10.1093/hmg/ddab007

Functional and adaptive significance of promoter mutations that affect divergent myocardial expressions of TRIM72 in primates

Feng Y, Xu H, Liu J, Xie N, Gao L, He Y, Yao Y, Lv F, Zhang Y, Lu J, Zhang W, Li CY, Hu X, Yang Z, Xiao RP.

Molecular Biology and Evolution. 2021; 38(7):2930-2945.

PMID: 33744959 | DOI: 10.1093/molbev/msab083

Upregulation of MG53 induces diabetic cardiomyopathy through transcriptional activation of peroxisome proliferation-activated receptor α

Liu F, Song R, Feng Y, Guo J, Chen Y, Zhang Y, Chen T, Wang Y, Huang Y, Li CY, Cao C, Zhang Y, Hu X, Xiao RP.

Circulation. 2015; 131(9):795-804.

PMID: 25637627 | DOI: 10.1161/CIRCULATIONAHA.114.012285